Microtubule-binding protein FOR20 promotes microtubule depolymerization and cell migration
نویسندگان
چکیده
منابع مشابه
Microtubule depolymerization promotes particle and chromosome movement in vitro
We have developed a system for studying the motions of cellular objects attached to depolymerizing microtubules in vitro. Radial arrays of microtubules were grown from lysed and extracted Tetrahymena cells attached to a glass coverslip that formed the top of a light microscope perfusion chamber. A preparation of chromosomes, which also contained vesicles, was then perfused into the chamber and ...
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Polarity protein complexes function during polarized cell migration and a subset of these proteins localizes to the reoriented centrosome during this process. Despite these observations, the mechanisms behind the recruitment of these polarity complexes such as the aPKC/PAR6α complex to the centrosome are not well understood. Here we identify Hook2 as an interactor for the aPKC/PAR6α complex tha...
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ژورنال
عنوان ژورنال: Cell Discovery
سال: 2017
ISSN: 2056-5968
DOI: 10.1038/celldisc.2017.32